🔗 Share this article Patients Coming Off Slimming Jabs Gain Back Pounds Far More Rapidly Than People Using Diet and Exercise Obesity treatment involves ongoing approaches. New research reveals that individuals who stop using popular slimming jabs like Wegovy and Mounjaro can put back on lost weight at a significantly accelerated pace than those who halt conventional diet and exercise programs. Published data in a leading health publication demonstrates that while overweight individuals frequently drop about a fifth of their total mass while on the medication, the mass is regained at an estimated rate of 0.8 kg per month once they quit. "Users buying such medications should be aware of the danger of quick rebound weight gain when the medication ends," cautioned expert Dr. Susan Jebb. Such speed of regain implies a reversion to starting mass within about a year and a half. Weighing Treatments The research, which examined dozens of studies involving thousands of patients, compared the results of these new drugs with other pills. The team emphasize that people who lose weight through diet and exercise typically see a slower creep back—around 100 grams monthly—once they finish. Understanding the Fast Regain Doctors propose the mode of action of the drugs is key to understanding the heightened regain. These medications mimic a natural hormone called glucagon-like peptide-1, which helps regulate appetite. "Long-term administration of the hormone levels several times higher than normal may cause the body to generate a reduced amount of its own natural GLP-1, and may also diminish sensitivity to its actions," said Dr. Adam Collins, a dietetics expert. "Discontinuation of this hormone supplement results in hunger is no longer kept in check, making overeating much more probable." An Ongoing Issue? The NHS advise the injections for people with weight-linked health risks, alongside prescribed lifestyle changes. A number of clinicians say that, due to the high risk of weight regain, the treatment is often ongoing. This view is reinforced by drug manufacturers, who note that the findings "underscore the long-term character of excess weight," comparing it to managing conditions like high blood pressure. User Accounts People who have come off the jabs describe a powerful return of appetite. "It was like a switch that goes on and I was suddenly starving," recalled an individual. The struggle is compounded if individuals have not established lasting dietary or behavioural modifications during treatment. Significant Use Recent estimates show that millions of adults in the UK have used these injections in the last 12 months, with demand remaining high. Adoption is higher among females than men. The 40s and 50s demographic shows the highest level of interest. A large proportion obtain the medications through private healthcare rather than the NHS. Ultimately, researchers stress that while the jabs are powerful tools for weight loss, they are not a standalone cure and lasting health benefits relies on combined lifestyle management.
Obesity treatment involves ongoing approaches. New research reveals that individuals who stop using popular slimming jabs like Wegovy and Mounjaro can put back on lost weight at a significantly accelerated pace than those who halt conventional diet and exercise programs. Published data in a leading health publication demonstrates that while overweight individuals frequently drop about a fifth of their total mass while on the medication, the mass is regained at an estimated rate of 0.8 kg per month once they quit. "Users buying such medications should be aware of the danger of quick rebound weight gain when the medication ends," cautioned expert Dr. Susan Jebb. Such speed of regain implies a reversion to starting mass within about a year and a half. Weighing Treatments The research, which examined dozens of studies involving thousands of patients, compared the results of these new drugs with other pills. The team emphasize that people who lose weight through diet and exercise typically see a slower creep back—around 100 grams monthly—once they finish. Understanding the Fast Regain Doctors propose the mode of action of the drugs is key to understanding the heightened regain. These medications mimic a natural hormone called glucagon-like peptide-1, which helps regulate appetite. "Long-term administration of the hormone levels several times higher than normal may cause the body to generate a reduced amount of its own natural GLP-1, and may also diminish sensitivity to its actions," said Dr. Adam Collins, a dietetics expert. "Discontinuation of this hormone supplement results in hunger is no longer kept in check, making overeating much more probable." An Ongoing Issue? The NHS advise the injections for people with weight-linked health risks, alongside prescribed lifestyle changes. A number of clinicians say that, due to the high risk of weight regain, the treatment is often ongoing. This view is reinforced by drug manufacturers, who note that the findings "underscore the long-term character of excess weight," comparing it to managing conditions like high blood pressure. User Accounts People who have come off the jabs describe a powerful return of appetite. "It was like a switch that goes on and I was suddenly starving," recalled an individual. The struggle is compounded if individuals have not established lasting dietary or behavioural modifications during treatment. Significant Use Recent estimates show that millions of adults in the UK have used these injections in the last 12 months, with demand remaining high. Adoption is higher among females than men. The 40s and 50s demographic shows the highest level of interest. A large proportion obtain the medications through private healthcare rather than the NHS. Ultimately, researchers stress that while the jabs are powerful tools for weight loss, they are not a standalone cure and lasting health benefits relies on combined lifestyle management.